What is Urine Toxicology?

Urine toxicology is the process of screening urine to determine the type and relative amount of legal and illegal substances a person has consumed. The test is performed to evaluate patients prior to receiving medicine therapy, patients in substance abuse recovery, patients displaying deviant drug behavior, obstetric patients, and patients using controlled medications. Toxicology tests, or tox screens, can detect a specifically targeted substance or up to 80 substances at once.

urine toxicology lab

How does Urine Toxicology work?

Medical professionals obtain urine samples from patients using clean-catch midstream urine collection. The patient will need to have thoroughly washed hands before opening the collection cup. Before urinating, the patient will wipe the urethral orifice to ensure the sample is not contaminated with foreign materials. When the sample is collected, the laboratory technician, nurse, or physician will label the sample to be evaluated by Harvest Labs.

Our lab uses two types of urine drug screening, immunoassay and gas chromatography/mass spectrometry, or GC/MS. Immunoassay does not measure the substance levels individually. It detects whether the substance is in the system by measuring drug levels in nanograms per milliliter with either a positive or negative result. GC/MS is capable of measuring exact levels of the substance found in the sample and is typically used to confirm a positive result.

We Offer Test Results For The Following Drugs:


  • Amitriptyline
  • Duloxetine
  • Olanzipene
  • Clomipramine
  • Fluoxetine
  • Sertraline
  • Doxepin
  • Imipramine
  • Venlafaxine


  • Bath Salts / Cathinones Panel
  • Ecstasy
  • Kratom / Mitragynine Panel
  • PCP
  • Cocaine
  • Alchohol (EtG / EtS)
  • Marijuana (THC)
  • Synthetic Marijuana Panel
  • Cotinine (Nicotine Metabolite)
  • Heroin (6-MAM)
  • Methamphetamine


  • Alprazolam
  • Diazepam
  • Lorazepam
  • Temazepam
  • Citalopram
  • Flunitrazepam
  • Midazolam
  • Triazolam
  • Clonazepam
  • Flurazepam
  • Oxazepam

Opiates / Opioids

  • Buprenorphine
  • Hydrocodone
  • Methadone
  • Oxymorephone
  • Tramadol
  • Codeine
  • Hydromorphone
  • Morphine
  • Propoxyphene
  • Fentanyl
  • Meperidine
  • Oxycodone
  • Tapentadol


  • Amobarbital
  • Secobarbital
  • Butalbital
  • Phenobarbital

Muscle Relaxants / Anticonvulsants

  • Carisoprodol
  • Pregabalin
  • Cyclobenzaprine
  • Gabapentin

Opiate Antagonists

  • Naloxone
  • Naltrexone


  • Ketamine
  • Zolpidem
  • Zopiclone


  • Amphetamine
  • Methylphenidate
  • Lisdexamphetamine
  • Phentermine
  • Methamphetamine

When Time Is Of The Essence, Count on Us For Fast Results

Reference Partnership Options Available

Oftentimes, physicians and hospitals would like to offer testing & toxicology services through their facility but don’t want the headache of managing equipment or overhead costs associated with running a laboratory internally. To solve this issue, a physician or hospital can set up a reference laboratory on-location by partnering with Principle Laboratory to contract out all of their testing needs. By partnering with us, a reference lab can effectively offer our entire portfolio of testing services to its patients.

Generate Additional Revenue By Expanding Your Test Menu

Our reference service allows on-premise labs to offer a larger variety of testing. We work behind the scenes as a silent partner with you exclusively and do not communicate with your customers unless requested to do so by you.

Learn More About Reference Partnership  

Requisition Form PDF Downloads

If you’re in a bind and need requisition forms immediately, we offer PDF forms that you can download and print to hold you over until your supplies order arrives:

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